How it Works
NJ Pet Safety • Flea & Tick Pills • Isoxazoline Awareness
🐾 Pet Owners First ⚠️ Know the warning signs 🌿 Reduce ticks at the source 🏡 New Jersey yard protection

Flea & Tick Pills and Seizure Warnings: What New Jersey Pet Owners Should Know (and Safer Ways to Reduce Tick Pressure)

If you’ve ever Googled “Are flea and tick chewables safe?” after seeing a scary story online, you’re not alone. Many popular flea & tick pills use isoxazoline class ingredients. These products help many pets — but some dogs and cats have reported neurologic side effects. Here’s a clear, practical guide for NJ families, plus a “reduce ticks at the source” plan that protects your yard without harsh synthetic pesticides.

Updated: December 25, 2025 Written by: Laurie White Topic: Pet safety + tick prevention
Laurie White, Founder Of Bite Back Tick &Amp; Mosquito Control
Laurie White Founder of Bite Back Tick & Mosquito Control • Family-first, all-natural protection for New Jersey yards
Important: This article is educational, not medical advice. If your pet has symptoms like shaking, wobbliness, or a seizure, contact a veterinarian immediately.

What’s “Really Inside” Many Flea & Tick Pills?

Many monthly (or longer-lasting) flea & tick chewables use isoxazoline class ingredients. They’re designed to kill fleas and ticks after the parasite bites and ingests the medication in your pet’s blood. That approach can be effective — but because these products are systemic, they also circulate through the body.

Common isoxazoline examples (ask your vet which ingredient your pet uses)

  • Afoxolaner (often associated with NexGard)
  • Fluralaner (often associated with Bravecto)
  • Sarolaner (often associated with Simparica / some combo preventatives)
  • Lotilaner (often associated with Credelio)

If you’re not sure what your dog or cat is taking, look at the box label or receipt, or ask your veterinarian for the active ingredient name. Knowing the ingredient matters — because side effect notes and cautions are often written around the drug class.

What the FDA Has Flagged About Isoxazoline Flea & Tick Products

The FDA has warned pet owners and veterinarians about the potential for neurologic adverse events reported in some dogs and cats treated with isoxazoline-class flea & tick drugs. Reported reactions include:

  • Muscle tremors (shaking)
  • Ataxia (wobbliness / unsteady walking)
  • Seizures
Key point most families miss: the FDA notes that seizures may occur even in animals without a prior history. That’s why it’s worth talking through your pet’s risk profile with your vet — especially if your pet is older, has ever had neurologic symptoms, or you’ve noticed unusual behavior after dosing.

What to do if your pet has a reaction

  1. Call your veterinarian immediately and describe what you’re seeing.
  2. Do not re-dose unless your veterinarian directs you to.
  3. Save the packaging (product name + lot info) and write down timing and symptoms.
  4. Ask your vet about reporting the hint of an adverse event so it can be tracked.

Why Some NJ Pets May Be More Sensitive

Every pet is different. Some tolerate systemic preventatives with no issues. Others may be more sensitive — and it’s not always predictable. Families often ask us if small dogs, seniors, anxious dogs, or pets with a seizure history are “higher risk.” The safest answer is: talk to your vet about your pet’s medical history and the best option for your situation.

A Safer, Smarter Strategy: Reduce Ticks in the Yard (So Your Pet Isn’t the “Tick Magnet”)

Here’s the part most people overlook: a huge chunk of tick exposure happens before any pill has a chance to help. Ticks are crawling in from wildlife and hiding in shaded, humid micro-zones — then hitching a ride on dogs, cats, and humans. If you reduce tick pressure on the property, you reduce the number of “tick encounters” in the first place.

Step 1: Make your yard less tick-friendly

  • Keep grass cut and edges trimmed (ticks love shade + humidity).
  • Blow back leaf litter and keep mulch/groundcover from creeping into play areas.
  • Move wood piles away from the home and keep them dry (rodents = ticks).
  • Limit deer highways: clean up brushy corridors and consider fencing/deterrents where appropriate.

Step 2: Do quick “tick checks” that actually catch problems

  • After walks, check ears, collar line, armpits, belly, tail base, and between toes.
  • Brush out coats and use a lint roller on legs/ankles after yard time.
  • For kids: check hairline, behind ears, waistbands, and socks.

Step 3: Protect the property with all-natural tick & mosquito control

Bite Back Tick & Mosquito Control helps NJ families reduce ticks at the source using an all-natural, essential-oil–based approach — without relying on the harsh synthetic pesticides many programs still use. We focus on the zones ticks and mosquitoes actually live:

  • Wood lines and shaded edges
  • Fence lines, stone borders, and dense landscaping
  • Under decks, playsets, sheds, and dog-run perimeters
  • Leafy groundcover and high-moisture pockets
Big benefit for pet owners: When you lower tick pressure on the property, your pet has fewer tick encounters — and your family can have a calmer, more informed conversation with your veterinarian about the prevention approach that fits your pet.

New Jersey Tick Reality: Why “One Dose” Doesn’t Solve the Whole Problem

In towns like Manalapan, Marlboro, Freehold, Howell, Colts Neck, Old Bridge, Jackson, and throughout Monmouth & Ocean County, ticks are constantly reintroduced by deer, mice, squirrels, rabbits, birds, and neighborhood pets. One deer cutting across a yard can drop ticks along a path — and those ticks wait in shaded vegetation for the next host.

When to call a vet right away

  • Seizure activity, collapse, severe tremors, or severe wobbliness
  • Sudden disorientation or unusual aggression/fear
  • Rapid worsening symptoms after a new medication dose
  • Any symptom that worries you as the owner — trust your gut

FAQ: Flea & Tick Pills, Side Effects, and Natural Tick Prevention

Should I stop my pet’s flea & tick pill immediately?

If your pet is having concerning symptoms, contact a veterinarian immediately. If your pet is doing well on a product, don’t panic — talk with your vet about your pet’s history and whether an isoxazoline-class product is the right match.

Can a dog have a seizure without any previous seizure history?

It’s possible for seizures to occur even without a prior history. If your dog has ever had neurologic symptoms (even mild), discuss that history with your veterinarian before choosing a flea/tick medication.

Do “natural” sprays and essential oils work on pets?

Some plant-based repellents can help, but pets can also be sensitive — especially cats. Only use products specifically labeled for your pet species, follow directions carefully, and consult your veterinarian if you’re unsure.

Is yard treatment enough by itself?

Yard treatment can significantly reduce tick pressure and mosquito activity, but no single step is perfect. The strongest plan combines yard protection, habitat cleanup, and tick checks — plus the vet guidance that fits your pet.